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Oxymetazoline Online for Sinus Infections and Headaches (Generic Afrin®)

(Generic Propecia©)

Stop sinus infection symptoms fast, like headache, runny nose and sneezing, with oxymetazoline(generic Afrin®) nasal spray from RedBox Rx. An affordable online consultation with an experienced, U.S. licensed medical provider will help you discover if prescription treatment is right for you.

  1. $10 per treatment 30 mL

Sorry, we’re closed for today. Our U.S. licensed medical providers are available daily 7 a.m. to 9 p.m. CST via live video visit. We look forward to serving you soon. Email us anytime at [email protected].

Oxymetazoline - Redbox Rx

Oxymetazoline FAQs

  • Oxymetazoline nasal spray is used to relieve nasal discomfort caused by colds, allergies and hay fever. It is also used to relieve sinus congestion and pressure. Oxymetazoline is in a class of medications called nasal decongestants. It works by narrowing the blood vessels in the nasal passages.

  • Oxymetazoline comes as a solution (liquid) to spray into the nose. It is usually used every 10 to 12 hours as needed, but not more often than twice in a 24-hour period. Follow the directions on the package label or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use oxymetazoline nasal spray exactly as directed. Do not use more or less of it, or use it more often than prescribed by your doctor or directed on the label.

    If you use oxymetazoline nasal spray more often or for longer than the recommended period of time, your congestion may get worse or may improve but come back. Do not use oxymetazoline nasal spray for longer than three days. If your symptoms do not get better after three days of treatment, stop using oxymetazoline and call your doctor.

    Oxymetazoline nasal spray is only for use in the nose. Do not swallow the medication.

    To prevent the spread of infection, do not share your spray dispenser with anyone else. Rinse the tip of the dispenser with hot water or wipe it clean after you use it.

    Follow the directions for using the nasal spray that appear on the package label. If you are using a product that comes in a pump dispenser, press down on the rim several times before using your first dose to prime the pump according to the directions on the label. When you are ready to use the spray, hold your head upright without tilting and place the tip of the bottle in your nostril. For the nasal spray, squeeze the bottle quickly and firmly. For products that come in a pump dispenser, press down on the rim with a firm, even stroke and breathe in deeply.

  • Oxymetazoline begins working seconds after use and effects can last up to 12 hours.[1]


  • Oxymetazoline nasal spray comes in 0.05% dosage.[2]


  • You can buy oxymetazoline online or in person at a retailer. Oxymetazoline is available over the counter in the 0.05% strength nasal spray.[2]


  • Oxymetazoline costs $10 per treatment with RedBox Rx. No insurance required.

  • Before using oxymetazoline:

    • Tell your doctor and pharmacist if you are allergic to oxymetazoline or any other medications.

    • Tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, EMSAM, Zelapar) or tranylcypromine (PARNATE).

    • Tell your doctor if you have or have ever had high blood pressure, diabetes, difficulty urinating due to an enlarged prostate gland, or thyroid or heart disease.

    • Tell your doctor if you are pregnant, plan to become pregnant or are breastfeeding. If you become pregnant while using oxymetazoline nasal spray, call your doctor.

  • Unless your doctor tells you otherwise, continue your normal diet.

  • This medication is usually used as needed. If your doctor has told you to use oxymetazoline regularly, use the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not use a double dose to make up for a missed one.

  • Oxymetazoline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

    • Burning.

    • Stinging.

    • Increased nasal discharge.

    • Dryness inside the nose.

    • Sneezing.

    • Nervousness.

    • Nausea.

    • Dizziness.

    • Headache.

    • Difficulty falling asleep or staying asleep.

    Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:

    • Fast heartbeat.

    • Slow heartbeat.

    Oxymetazoline nasal spray may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

  • Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat, light and moisture (not in the bathroom). Do not freeze the medication.

    Unneeded medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community.

  • If you use too much oxymetazoline nasal spray or if someone swallows the medication, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

  • Ask your pharmacist any questions you have about oxymetazoline nasal spray.

    It is important for you to keep a written list of all the prescription and nonprescription (over the counter) medicines you are taking, as well as any products such as vitamins, minerals or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

  • Brand names for oxymetazoline include:

    • Afrin® Nasal Spray

    • Anefrin® Nasal Spray

    • Dristan® Nasal Spray

    • Mucinex® Nasal Spray

    • Nostrilla® Nasal Spray

    • Vicks Sinex® Nasal Spray

    • Zicam® Nasal Spray

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How we help you

It is time to start thinking outside the healthcare box. Our medical and pharmacy teams provide the individualized care you need when you need it. All completely online. It is quality, trusted treatment with affordable convenience including:

  • FDA approved prescription treatments
  • Easy online visits on your own time
  • U.S. licensed medical providers
  • FREE delivery in discreet packaging

Sorry, we’re closed for today. Our U.S. licensed medical providers are available daily 7 a.m. to 9 p.m. CST via live video visit. We look forward to serving you soon. Email us anytime at [email protected].

How RedBox Rx Works

  • Select the condition you would like to treat.

    Choose either a specific treatment or condition. Then fill out a quick questionnaire about your health history.

  • Get your personalized treatment plan.

    After a review by a U.S. licensed medical provider, you will receive recommended treatment options so you can complete the prescription order for your medication.

  • Prescriptions delivered right to your door.

    If your provider prescribes treatment, we will ship it to you for free in discreet packaging from our U.S. licensed pharmacy.

RedBox Rx is here when you need us with out-of-the-box personalized care.

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